Dr. Styner also alerted that reduced calorie intake can increase the risk of fracture as well as negatively affect bone strength. The study was concentrated upon bone marrow fat. Though still scientists are not been able to understand how fat works, but they do think that it does affect health in mammals and humans.
Earlier studies as per Dr. Styner had revealed that bone marrow fat and bone health were related to each other in a way that when the high-calorie intake leads to obesity and further increased the levels of bone marrow fat. Also, when obese as well as mice with normal weight exercised, it leads to an increase in bone density due to the decrease in bone marrow fat.
The objective of the study was to find out how a decrease in calorie intake can affect the bone marrow fat as well as bone health. The research involved two groups of mice. One of the groups was fed 30% fewer calories as compared to the other group. The other group was offered a regular calorie diet.
The mice that were on restricted calories also received mineral and vitamin supplements in order to keep the nutrient intake at par with the other normal calorie intake ones. The groups were further split in 6 groups, the sedentary ones, and the exercising ones. The results showed that the mice that were kept on a calorie-restricted diet seem to not only lost weight but also showed a reduction in bone density and an increase in bone marrow fat as well.
The researchers were surprised to see that bones became fragile due to the restriction of calories. Though the investigations are not complete yet and further research needs to be done in order to understand the bone marrow functioning, the team did find that reduction in calories leads to a decrease in bone marrow fat at the same time affecting the quantity and quality of bone.